mental-health

The role of the dorsolateral prefrontal cortex in ego dissolution and emotional arousal during the psychedelic state

Here is the link to the full article (pre-print). Abstract: Lysergic acid diethylamide (LSD) is a classic serotonergic psychedelic that induces a profoundly altered conscious state. In conjunction with psychological support, it is currently being explored as a treatment for generalized anxiety disorder and depression. The dorsolateral prefrontal cortex (DLPFC) is a brain region that […]

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Healing through the body: The potential role of Daoist meditation in psychedelic therapy

Here is the link to the full article (pre-print). Abstract: Psychedelics are hallucinogenic drugs that have the potential to treat depression, post-traumatic stress disorder, and other psychiatric conditions. The dominant paradigm in contemporary psychedelic-assisted therapy is non-directive; that is, participants undergo the psychedelic treatment with minimal external guidance from therapists. However, the clinical outcomes of […]

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Psychedelics disrupt the functional hierarchy of the human brain

This was my PhD thesis! Here is the link to the full manuscript. Abstract: Psychedelics, such as lysergic acid diethylamide (LSD), N,N-dimethyltryptamine (DMT), and psilocybin, are hallucinogenic drugs that act on the 5-HT2A receptor. Their effects can be analysed on three different levels: (1) phenomenology, or subjective experience, as psychedelics strongly alter a person’s state […]

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LSD flattens the hierarchy of directed information flow in fast whole-brain dynamics

Currently in press at Imaging Neuroscience. Here is the full article. Abstract: Psychedelics are serotonergic drugs that profoundly alter consciousness, yet their neural mechanisms are not fully understood. A popular theory, RElaxed Beliefs Under pSychedelics (REBUS), posits that psychedelics flatten the hierarchy of information flow in the brain. Here, we investigate hierarchy based on the […]

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